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ₐ Thinking Like a Phage: The Genius of the Viruses That Infect Bacteria and Archaea for ipad ₩ Author Merry Youle ⃡

ₐ Thinking Like a Phage: The Genius of the Viruses That Infect Bacteria and Archaea for ipad ₩ Author Merry Youle ⃡ ₐ Thinking Like a Phage: The Genius of the Viruses That Infect Bacteria and Archaea for ipad ₩ Author Merry Youle ⃡ It isnt easy to be a phage First, what is a phage A phage is a virus that infects Bacteria To succeed, a phage must encounter, recognize, and enter a particular type of bacterial cell, then coerce it to make phages rather than cells Of course, the cell resists this hostile takeover in numerous ways, all of which the successful phage overcomes The triumphant phage then proceeds with its replicative business In this engaging book, Merry Youle relates some of the tactics used by 21 pheatured phages to outwit their host and successfully maintain their own lineage generation after generation.This ongoing contest of wits is a matter of life and death for both players A phage chromosome arriving in its intended host cell is met by the cells state of the art defenses Unless it dodges or neutralizes every one, it will be chopped into a nutritious snack for the cell If the phage survives, it then quickly diverts the cells machinery to production of phages, rather than cells Under skillful phage supervision, manufacture of phage components proceeds at top speed, with all parts produced when needed and in the quantities required As the pieces come off the assembly line, they self assemble into sophisticated transport packages, each carrying a phage chromosome and capable of delivering it into a new host cell When a new crop of progeny is ready perhaps 25, 100, or of them the phage ruptures the cell to free them all and send them out into the world in quest of hosts of their own Overall, a balance is maintained so that both the phages and their hosts thrive.Many phages have the option to instead follow a different script When they arrive in a host, they can opt to delay immediate hostile takeover and to instead form a coalition with the host for mutual benefit In this case, as the cell grows and divides, the phage is replicated and inherited by both daughter cells This can continue for many generations However, if the cell encounters life threatening difficulties, the phage ends the alliance and switches to rapid replication Cell rupture and release of the new generation follows quickly.Each step of the way presents challenges that test the ingenuity of the phages In this book, tales of phage prowess are accompanied by pertinent electron micrographs every chapter is enlivened by informative illustrations created by San Diego fine artist Leah Pant a The writing focuses on strategies and underlying principles, with a minimum of jargon Since some knowledge of molecular biology is required to appreciate phage wizardry, a primer of the needed basics is provided for those unfamiliar with that subject Thus, these phage adventures can be enjoyed by a wide audience.Despite being the most abundant life form, the phages being much smaller than even the microbes they infect elude our everyday perception Thinking Like a Phage offers a tour of this unseen dimension of life on Earth Whether you are an expert or new to the phage world, these vignettes drawn from phage life will intrigue you Awareness of this vast, creative, yet invisible realm can enrich your appreciation for the living world of which we, as Homo sapiens , are only a small part. 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    • Thinking Like a Phage: The Genius of the Viruses That Infect Bacteria and Archaea
    • 3.1
    • 255
    • Kindle
    • 310 pages
    • 0990494314
    • Merry Youle
    • English
    • 06 July 2016

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